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Cancer pancreas, You will need to cover your head

Women’s quality of life improves when they dress appropriately for such a delicate disease.

Pancreatic cancer or pancreatic cancer is a tumor that originates in the pancreatic gland.

It is one of the most aggressive neoplasms due to its early dissemination, its lack of specific early symptoms and its late diagnosis (at the time of diagnosis, patients usually have locally advanced and even metastatic disease, which prevents curative surgery ). In recent years, new techniques to help the early detection of pancreatic cancer have been studied.1

Pancreatic cancer, although it is the tenth tumor in frequency in industrialized countries (only 2% to 3% of all solid tumors), is the fourth leading cause of death from cancer and is expected to increase its incidence by 2030 By 50%, making it the second leading cause of cancer death and causing more deaths than prostate, colon or breast cancer.2

 

For this reason, advances in the fight against this disease, such as new and more effective chemotherapy regimens, 2 earlier diagnostic methods, 3 drug development and specific molecules4 and advances in Curative surgery.6 Even the effectiveness of immunotherapy is being demonstrated.7 All this is resulting in a progressive improvement in survival over the last decade.

Classification [edit]
More than 90% of pancreatic tumors correspond to pancreatic ductal adenocarcinoma (ADP), 8 which are very aggressive and have very poor prognosis.9 The rest of pancreatic neoplasms are mainly acinar adenocarcinoma, pancreatic neuroendocrine tumors such as insulinoma, cystic tumors, Pseudopapillary carcinoma and pancreatoblastoma, 8 which have a different diagnosis and treatment, with a better general prognosis.

Phases [edit]
The disease is grouped, according to its development, in the following stages or stages: 10

Stage I: The tumor is limited to the pancreas with a size equal to or less than 2 cm.
Stage II: The tumor is limited to the pancreas with a size larger than 2 cm.
Stage III: The tumor extends outside the pancreas, but does not invade the celiac trunk or the superior mesenteric blood vessels.
Stage IV: the tumor is inoperable, as it invades the celiac trunk or the superior mesenteric vessels.
Epidemiology [edit]
The annual global prevalence for pancreatic cancer is about 8/100 000 people. Incidence rates fluctuate across countries, with variations varying approximately five to seven times between countries with the lowest and highest incidence. The rates reported in African countries are lower because of the scarcity of data. We have searched to determine the environmental factors that could explain this variation. In addition to the country-specific differences, there are subtle geographical and regional differences. Countries at or near the equator have the lowest rates.11

In 2000, the global incidence was 217 000 new cases, with a mortality of 213 000.8 In 2008, an estimated 279 000 new diagnoses of pancreatic cancer were recorded worldwide, representing 2.2 % Of all new cancers.11 In 2010, about 43,000 people were diagnosed with pancreatic cancer in the United States.12

Pancreatic adenocarcinoma (ADP) is the second most common gastrointestinal malignancy. It represents the fourth leading cause of cancer death in adults, with an incidence that increases after age 45. It is more common in men than in women (ratio of 1.3: 1). In terms of races, their prevalence is higher in blacks. It is one of the most lethal human cancers and one of the most difficult to treat.8

Etiology [edit]
The etiology and mechanism of pancreatic carcinogenesis are still unknown. It is believed that the process is initiated by an alteration of the cells of the pancreatic ducts. Carcinogens would reach these cells causing malignant transformation through three possible access routes: biliary reflux, duodenal reflux, or via blood.

Risk Factors [edit]
The following are the main known risk factors for pancreatic cancer, although in many cases the patient has developed the disease without being or has been exposed to any of them, so further research is needed to study in depth the origin of pancreatic cancer. This tumor.

Tobacco [edit]
It is suspected to account for between 20-30% of cases.13 Other estimates show 27% in men and 11% in women.14 The risk of tobacco users (smokers) increases by 75% compared to That of the non-consumers and subsists increased for a minimum of 10 years after leaving the habit.13 The time of exposure contributes to increase the chances of developing a

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